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Statistics

Ignet has analyzed abstracts from millions of publications available in PubMed.

Specifically, Ignet has found 573167 gene-gene interactions from 360283 sentences in 219004 PubMed publications. These interactions involve 11817 unique human genes.


An example listed for gene interaction with IFNG:

1473 genes associated with IFNG,

Top 50 genes ranked by four scores

Rank Degree centrality Eigenvector centrality Closeness centrality Betweenness centrality
1 EGF MME GPR98 PLAT
2 ERBB2 TAC1 CNBP ID2
3 EGFR ERBB2 CUBN IL6
4 ZFP36 EGF CSPG4 SOD1
5 SRC EGFR CXADR MITF
6 SPINK1 VEGFA FEV CD4
7 PRSS1 NOS2A KATNB1 ERBB2
8 PRSS3 ZFP36 DAO SRC
9 ID2 DCX TFAP2B IL2
10 DCX NGF IRX3 EGFR
11 NGF POMC SCN1A IFNG
12 VEGFA AVP PFKL IRF4
13 NOS2A NPPA RDX PTEN
14 PLAT PLAT NTN4 VWF
15 POMC ID2 EPHA7 PPARG
16 AVP SRC ISCU CD8A
17 NPPA PRSS1 GPS1 AGT
18 MME SPINK1 VEZT MS
19 TAC1 PRSS3 MIRN124-3 TNF
20 IL6 EPO THAP5 EPO
21 LYN IL6 AP2B1 ABL1
22 BMI1 KIT BCAR3 IL4
23 CD4 SST PDZD7 AKT1
24 TNF COL1A1 SLC5A3 SGK1
25 EPO PPARG TPST2 DNMT1
26 IFNG SERPINE1 GAL REN
27 PPARG PLG KIF1B CASP3
28 MITF NKX2-5 ALAS1 MCL1
29 SOD1 TBX5 MELAS GJA1
30 KIT IL10 ALDH5A1 TNFSF10
31 PDGFA REN DLL4 CLS
32 SST SELL CKS2 TSC2
33 COL1A1 TIMP1 MCF2L MPO
34 NKX2-5 ELN EFNA5 AVP
35 TBX5 BDKRB1 TSIX MAPK1
36 PLG FSTL1 IRX6 INS
37 SERPINE1 BMP4 MIRN122 SST
38 IL2 MAPK1 SLC6A1 COL1A1
39 MS TNF PDLIM4 IL2RA
40 MAPK1 CSF1 TRDMT1 IL5
41 CD8A TNFSF11 MCOLN3 POMC
42 VWF NFKB1 AKR1D1 NPPA
43 CRP PDGFB TRPV4 MET
44 HBB BCR LRP2 NPR1
45 FAM126A SLC47A2 PSMD10 ACE
46 STAT3 SLC22A2 CDK7 PDGFA
47 INS ABL1 HDAC11 VEGFA
48 IL4 CYP2B6 HADHB NOS2A
49 PTEN ALPI SETD1B TSC1
50 IRF4 TBXAS1 SETD1A MUC5AC