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Statistics

Ignet has analyzed abstracts from millions of publications available in PubMed.

Specifically, Ignet has found 573167 gene-gene interactions from 360283 sentences in 219004 PubMed publications. These interactions involve 11817 unique human genes.


An example listed for gene interaction with IFNG:

1473 genes associated with IFNG,

Top 50 genes ranked by four scores

Rank Degree centrality Eigenvector centrality Closeness centrality Betweenness centrality
1 ERBB2 EGF TFAP2B ID2
2 ID2 MME TRMU PLAT
3 ID2 NPPA ABAT PLAT
4 NOS2A EGFR AMD1 ID2
5 SRC EGF AMOT IL6
6 ERBB2 ERBB2 MEG3 SOD1
7 NOS2A AVP COQ7 SOD1
8 VEGFA ERBB2 HDAC2 MITF
9 VEGFA ERBB2 PDZD7 CD4
10 ERBB2 EGFR SCN9A ERBB2
11 ZFP36 ZFP36 PFKL SRC
12 ERBB2 NOS2A IRX6 SRC
13 EGFR ERBB2 BCAR3 IL2
14 ERBB2 VEGFA DMPK EGFR
15 NPPA EGFR AIC IFNG
16 MME ERBB2 MAP1S IRF4
17 MME ERBB2 ATXN8OS IL2
18 EGFR EGFR ALDH1A2 ERBB2
19 TAC1 POMC GJB3 PTEN
20 PLAT NOS2A GPS1 EGFR
21 ERBB2 NGF IRX3 VWF
22 EGF VEGFA PAFAH1B1 PPARG
23 SPINK1 ERBB2 PAFAH2 CD8A
24 PRSS1 DCX MCM8 AGT
25 PRSS3 TAC1 MCF2L SRC
26 NGF MME DAO PPARG
27 EGFR PLAT THAP5 MS
28 EGF ID2 MIRN124-3 AGT
29 ERBB2 ID2 EVI1 TNF
30 POMC PLAT CKS2 AGT
31 PLAT SRC MIRN122 EGFR
32 SRC SRC LHX1 IFNG
33 AVP SPINK1 AADAC EPO
34 EGFR PRSS3 NFU1 EPO
35 DCX PRSS1 EFNA5 IFNG
36 IL6 EPO ATP1B1 ABL1
37 BMI1 EPO TSIX IL4
38 LYN IL6 MRPS6 AKT1
39 LYN NPPA HADHA TNF
40 BMI1 SRC ATP4A SGK1
41 CD4 KIT VEZT TNF
42 TNF KIT DLL4 REN
43 IL6 SST AP2B1 CASP3
44 EPO COL1A1 TPST2 TNF
45 EPO COL1A1 SLC5A3 ERBB2
46 IFNG PPARG COPS8 EGFR
47 PPARG NKX2-5 DAOA AGT
48 ERBB2 TBX5 DSC2 AGT
49 MITF SERPINE1 PTBP1 TNF
50 SOD1 TBX5 EKV MCL1