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Statistics

Ignet has analyzed abstracts from millions of publications available in PubMed.

Specifically, Ignet has found 573167 gene-gene interactions from 360283 sentences in 219004 PubMed publications. These interactions involve 11817 unique human genes.


An example listed for gene interaction with IFNG:

1473 genes associated with IFNG,

Top 50 genes ranked by four scores

Rank Degree centrality Eigenvector centrality Closeness centrality Betweenness centrality
1 ERBB2 MME CSPG4 PLAT
2 SRC ERBB2 RGS16 ID2
3 ERBB2 EGFR IRAK3 PLAT
4 PRSS3 VEGFA HDAC2 ID2
5 ERBB2 NOS2A KATNB1 IL6
6 TAC1 NOS2A TRPV4 SOD1
7 NOS2A ZFP36 PSMD10 SOD1
8 ID2 ERBB2 MCM8 MITF
9 VEGFA TAC1 SPECC1 CD4
10 SPINK1 VEGFA THAP5 ERBB2
11 MME EGF PFKL SRC
12 PRSS1 ERBB2 MCOLN3 SRC
13 EGF ERBB2 EKV IL2
14 ERBB2 EGFR RRM2B EGFR
15 ID2 ERBB2 TPH1 IFNG
16 NOS2A EGFR CDK7 IRF4
17 NGF DCX DSC2 IL2
18 VEGFA EGF AMD1 ERBB2
19 EGFR ERBB2 PAFAH1B1 PTEN
20 EGFR NPPA FNRBL EGFR
21 PLAT NGF CUBN VWF
22 ERBB2 ERBB2 CYP26B1 PPARG
23 ZFP36 MME CD97 CD8A
24 EGFR POMC LRP2 AGT
25 PLAT AVP HOXA9 SRC
26 EGF EGFR MIRN122 PPARG
27 AVP ID2 FEV MS
28 DCX ID2 SCN9A AGT
29 POMC PLAT AMOT TNF
30 MME PLAT GPR98 AGT
31 ERBB2 SRC ALDH1A2 EGFR
32 NPPA SRC BCAR3 IFNG
33 SRC PRSS3 TIE1 EPO
34 EGFR SPINK1 FCN2 EPO
35 ERBB2 PRSS1 GABARAPL1 IFNG
36 IL6 EPO AP2B1 ABL1
37 LYN EPO RLTPR IL4
38 BMI1 IL6 GALR1 AKT1
39 LYN KIT POLR3E TNF
40 BMI1 NPPA PFKM SGK1
41 CD4 SST IRX6 TNF
42 TNF KIT SLC6A13 REN
43 IL6 SRC DAOA CASP3
44 EPO COL1A1 NFU1 TNF
45 EPO COL1A1 DMPK ERBB2
46 IFNG PPARG CNBP EGFR
47 PPARG PLG PDZD7 AGT
48 ERBB2 NKX2-5 IRX3 AGT
49 MITF SERPINE1 AKR1D1 TNF
50 SOD1 TBX5 RDX MCL1