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Statistics

Ignet has analyzed abstracts from millions of publications available in PubMed.

Specifically, Ignet has found 573167 gene-gene interactions from 360283 sentences in 219004 PubMed publications. These interactions involve 11817 unique human genes.


An example listed for gene interaction with IFNG:

1473 genes associated with IFNG,

Top 50 genes ranked by four scores

Rank Degree centrality Eigenvector centrality Closeness centrality Betweenness centrality
1 VEGFA NOS2A PDZD7 ID2
2 SRC MME LHX1 PLAT
3 EGF ERBB2 COQ7 ID2
4 ERBB2 EGFR ISCU PLAT
5 PLAT MME ATP1B1 IL6
6 ERBB2 ERBB2 EVI1 SOD1
7 SRC EGF HOXA9 SOD1
8 EGF TAC1 THAP5 MITF
9 MME VEGFA MIRN124-3 ERBB2
10 ERBB2 EGF PAFAH1B1 SRC
11 TAC1 EGFR AP2B1 SRC
12 NOS2A ERBB2 SETD1B IL2
13 NOS2A AVP RRM2B EGFR
14 SPINK1 POMC NTN4 IFNG
15 VEGFA NPPA GPS1 IRF4
16 ZFP36 NOS2A ARVD1 IL2
17 EGFR ZFP36 PTBP1 ERBB2
18 DCX EGFR DAOA PTEN
19 EGFR ERBB2 VEZT EGFR
20 POMC VEGFA AIC VWF
21 ID2 ERBB2 KSS PPARG
22 ERBB2 EGFR LTB4R AGT
23 PRSS3 ERBB2 EPHA7 SRC
24 ID2 DCX BCAR3 PPARG
25 EGFR NGF HOXA10 MS
26 PRSS1 ERBB2 MIRN122 AGT
27 ERBB2 ID2 GJB3 TNF
28 ERBB2 PLAT RGS16 AGT
29 PLAT PLAT SLC6A1 EGFR
30 NGF ID2 TPST1 IFNG
31 EGFR SRC MRPS6 EPO
32 ERBB2 SRC TFAP2B EPO
33 MME PRSS3 GPR39 IFNG
34 AVP SPINK1 CKS1A ABL1
35 NPPA PRSS1 DSC2 IL4
36 IL6 EPO MCM8 AKT1
37 LYN EPO GALR1 TNF
38 LYN IL6 ALAS2 SGK1
39 BMI1 KIT IRX6 TNF
40 BMI1 SST ALDH1A2 REN
41 TNF SRC KIAA0157 CASP3
42 EPO NPPA ATXN8 TNF
43 EPO KIT VLDLR ERBB2
44 IL6 COL1A1 FEV EGFR
45 IFNG COL1A1 EFNA5 AGT
46 PPARG PPARG TSIX AGT
47 ERBB2 NKX2-5 PFKM TNF
48 MITF TBX5 PAFAH2 MCL1
49 SOD1 NKX2-5 MBL2 AKT1
50 SOD1 TBX5 KATNB1 AGT