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Statistics

Ignet has analyzed abstracts from millions of publications available in PubMed.

Specifically, Ignet has found 573167 gene-gene interactions from 360283 sentences in 219004 PubMed publications. These interactions involve 11817 unique human genes.


An example listed for gene interaction with IFNG:

1473 genes associated with IFNG,

Top 50 genes ranked by four scores

Rank Degree centrality Eigenvector centrality Closeness centrality Betweenness centrality
1 PRSS3 EGFR KIF1B ID2
2 EGF EGF ATXN8OS PLAT
3 EGFR NOS2A COPS8 PLAT
4 POMC ZFP36 PDLIM4 ID2
5 EGF VEGFA TIE1 IL6
6 ERBB2 ERBB2 ALAS1 SOD1
7 AVP EGFR RLTPR SOD1
8 NGF ERBB2 TRMU MITF
9 EGFR ERBB2 PAFAH2 CD4
10 PLAT ERBB2 GAL ERBB2
11 ID2 ERBB2 NTN4 SRC
12 ERBB2 ERBB2 RGS16 SRC
13 ERBB2 ERBB2 EPHA7 IL2
14 PLAT EGFR GABARAPL1 EGFR
15 ERBB2 DCX CD97 IFNG
16 EGFR NGF CXADR IRF4
17 SRC MME AMD1 IL2
18 TAC1 NPPA PFKM ERBB2
19 VEGFA MME CNBP PTEN
20 MME EGF DMPK EGFR
21 PRSS1 EGFR FNRBL VWF
22 ID2 POMC LRP2 PPARG
23 VEGFA VEGFA LZTS2 CD8A
24 SRC AVP LRPPRC AGT
25 ERBB2 NOS2A GALR1 SRC
26 SPINK1 TAC1 DAO PPARG
27 MME ID2 ARVD1 MS
28 ERBB2 PLAT RRM2B AGT
29 ZFP36 ID2 GPR98 TNF
30 ERBB2 PLAT IRX3 AGT
31 EGFR SRC SPECC1 EGFR
32 DCX SRC POLR3E IFNG
33 NOS2A PRSS1 ATXN8 EPO
34 NPPA SPINK1 ALAS2 EPO
35 NOS2A PRSS3 KIAA0157 IFNG
36 IL6 EPO VEZT ABL1
37 LYN EPO MIRN124-3 IL4
38 LYN IL6 KSS AKT1
39 BMI1 KIT BCAR3 TNF
40 BMI1 NPPA THAP5 SGK1
41 CD4 KIT PDZD7 TNF
42 TNF SRC TRPV4 REN
43 EPO SST AP2B1 CASP3
44 EPO COL1A1 DAOA TNF
45 IL6 COL1A1 PAFAH1B1 ERBB2
46 IFNG PPARG NFU1 EGFR
47 PPARG NKX2-5 MNAT1 AGT
48 ERBB2 TBX5 AKR1D1 AGT
49 MITF PLG COQ7 TNF
50 SOD1 SERPINE1 SLC5A3 MCL1